John 16:33 These things I have spoken unto you, that in me ye might have peace. In the world ye shall have tribulation: but be of good cheer; I have overcome the world.

Matthew Henry:  While we have God’s favourable presence, we are happy, and ought to be easy, though all the world forsake us.

Barnes:  In the world – Among the men to whom you are going. You must expect to be persecuted, afflicted, tormented.

JFB:  In the world ye shall have tribulation—specially arising from its deadly opposition to those who “are not of the world.”

Poole:  In the world ye meet with troubles, which you will certainly do, because the world hateth you.

Gill:  It is in him, and in him only, in his person, blood, righteousness, and sacrifice, which speak peace, pardon, and atonement, that a soul finds any true, solid peace, rest, comfort, and joy;

There is a peace by Christ, which he has made for his people by the blood of his cross;

and there is a peace in him, which is enjoyed through faith’s looking…

to his blood for pardon,

to his righteousness for justification,

to his sacrifice for atonement and satisfaction;

and by having communion with him,

and discoveries of his love,

and by seeing safety and security in him.

In the world ye shall have tribulation;

from the instance and example of Christ, who was all his life a man of sorrows;

from the conformity of the members to the head;

from the divine appointment that has so determined it;

from the natural enmity of the world to the saints;

from the experience of the people of God in all ages.

Pulpit:  Peace – adequate support amid the crushing force and vehement hostility of the world.

Luther:  “That is the last word given, and struck into their hand by way of good-night. But He concludes very forcibly with this, and therefore has He finished the entire discourse.”

Luther:  “He does not say: Be comforted, you have overcome the world, but this is your consolation, that I, I have overcome the world; my victory is your salvation.”

Meyer:  And upon this victor rests the imperishability of the church.